Resources

Resources

  • Publication

    What’s New In Treatment Monitoring: Viral Load And CD4 Testing

    Treatment initiation

    • ART should be initiated in all children, adolescents, pregnant and breastfeeding women and adults living with HIV, regardless of WHO clinical stage and at any CD4 cell count.
    • ART should be initiated in all children, adolescents, pregnant and breastfeeding
      women and adults living with HIV, regardless of WHO clinical stage and at any CD4 cell count.
    • As a priority, ART should be initiated in all children, adolescents and adults with severe or advanced HIV clinical disease and adults with a CD4 count ≤ 350 cells/mm3 as well as children < 5 years of age with WHO clinical stage 3 or 4 or CD4 count ≤ 750 cells/mm3.

     Author(s) WHO   Originally published on July 1, 2017   Posted on November 15, 2018


  • Publication

    Technical And Operational Considerations For Implementing HIV Viral Load Testing

    This publication provides high-level guidance on implementing and scaling up HIV viral load testing programmes for health ministries and implementation partners, using a three-phased approach: (1) planning; (2) scale-up; and (3) sustainability. The guidelines for managing antiretroviral therapy (ART) issued by WHO have recognized the importance of viral load monitoring since 2003. Routine viral load monitoring is now strongly
    recommended as the monitoring strategy of choice.

     Author(s) WHO   Originally published on July 1, 2014   Posted on November 15, 2018


  • Publication

    Considerations For Adoption And Use Of Multi-disease Testing Devices In Integrated Laboratory Networks

    Several new laboratory technologies are available or are being developed to allow for testing of different conditions using disease-specific tests on the same platform. For example, a single device may be able to test for the presence of tuberculosis (TB) and HIV, and quantitatively measure HIV and hepatitis C viral load by using disease-specific reagents or cartridges with self-contained nucleic acid testing technology. Some of these technologies are being designed for use at centralized reference laboratories while others
    may be positioned for use at or near to point of care.

     Author(s) WHO   Originally published on June 1, 2017   Posted on November 15, 2018


  • Publication

    Multidisease testing for HIV and TB using the GeneXpert platform: A feasibility study in rural Zimbabwe

    Ndlovu and colleagues demonstrated the feasibility of the GeneXpert multi-disease testing at the near point of care in district and subdistrict health settings in Zimbabwe

     Author(s) Ndlovu et al   Originally published on February 19, 2019   Posted on October 12, 2018


  • Publication

    Significant Patient Impact Observed Upon Implementation of Point-of-Care Early Infant Diagnosis Technologies in an Observational Study in Malawi

    In this Malawi study, ART initiation rates were significantly improved with the implementation of same-day POC EID testing compared with referred, longer-turnaround laboratory-based testing.

     Author(s) Mwenda et al   Originally published on February 19, 2019   Posted on October 12, 2018


  • Publication

    Effect of point-of-care early infant diagnosis on antiretroviral therapy initiation and retention of patients: a cluster-randomised trial

    In this cluster-randomized controlled trial, Jani et al. evaluated the effect of point-of-care (POC) early infant HIV testing on rates of antiretroviral therapy (ART) initiation and retention in care among HIV-positive infants who presented for early infant diagnosis at health facilities in Mozambique. POC achieved more rapidly diagnosis and timely provision of treatment to HIV-infected infants.

     Author(s) Jani et al   Originally published on February 19, 2019   Posted on October 12, 2018


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